Mojtaba Zarei

Director, Professor of Neurology and Neuroscience

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1991 M.D. (Doctor of Medicine), Shiraz University of Medical Sciences, Iran.  Thesis: Brain Electrical Activity Mapping. 

1996 Ph.D. in Neuroscience. Faculty of Medicine, King’s College, University of London, UK.   Thesis: An electrophysiological study of the effects of lesions of the rat primary somatosensory cortex in cortical reorganization and the fetal cortical transplants.

2001 MRCP (UK) - Membership of the Royal College of Physicians of the United Kingdom.

2005 Certificate of Completion of Specialty Training in Neurology, Postgraduate Medical Education and Training Board, UK.

2005 Cognitive and Movement Disorders, University of Cambridge, UK, and Center for Behavioural and Cognitive Neurology, Northwestern University, Chicago, USA

2006 Clinician-Scientist Fellow, Oxford Centre for Functional MRI, University of Oxford, UK

2010 Clinical Neurophysiology Fellowship, National Hospital for Neurology and Neurosurgery, University College London, UK

Membership of Scientific and Professional Organizations:

Member of the Royal College of Physicians of UK

Member of Association of British Neurologists

Member of Association of British Neuroscientists

Member of Association of European Neuroscientists

Member of Human Brain Mapping Organization

Member of International Brain Research Organization

Member of Iranian Neurology Association 



Clinical application of Functional Brain Mapping using MRI, MEG, EEG, PET

Study of Alzheimer, Parkinson and Multiple Sclerosis

Cognitive and Behavioural Neurology



  1. Eshaghi A, Riyahi-Alam S, Saeedi R, Roostaei T, Nazeri A, Aghsaei A, Doosti R, Ganjgahi H, Bodini B, Shakourirad A, Pakravan M, Ghana'ati H, Firouznia K, Zarei M, Azimi AR, Sahraian MA. Classification algorithms with multi-modal data fusion could accurately distinguish neuromyelitis optica from multiple sclerosis. Neuroimage Clin. 2015 Jan 9;7:306-14.
  2. Nazeri A, Ganjgahi H, Roostaei T, Nichols T, Zarei M; for the Alzheimer's Disease Neuroimaging Initiative. Imaging proteomics for diagnosis, monitoring and prediction of Alzheimer's disease. Neuroimage. 2014 Aug 28;102P2:657-665.
  3. Tabatabaei H, Ekhtiari H, Ganjgahi H, Hasani-Abharian H, Oghabian MA, Moradi F, Zarei M, Patterns of Brain Activation during Craving in Heroin Dependents Successfully Treated by Methadone Maintenance and Abstinence Based Treatments. Journal of Addiction Medicine, 2014, Mar-Apr;8(2):123-9.
  4. Zarei M, Ibarretxe-Bilbao N, Hough M, Junque C, Tolosa E, Marti MJ. Pattern of Cortical Thinning is Associated with Disease Stages and Dementia in Parkinson’s Disease. J Neurol Neurosurg Psychiatry. 2013 Aug;84(8):875-81
  5. Zarei M, Beckmann CF, Binnewijzend MAA, Schoonheim MM, Oghabian MA, Sanz-Arigita EJ, Scheltens P, Matthews PM, Barkhof F, Functional Segmentation of the Hippocampus in Human and Its Implications in Alzheimer’s Disease Neuroimage. 2012 Nov 3;66C:28-35.
  6. Eshaghi, A, Riyahi-Alam, M.S, Roostaei, T, Haeri, G, Aghsaei, A, Aidi, MR, Pouretemad, HR, Zarei, M, Farhang, S, Saeedi, R, Nazeri, A, Ganjgahi, H, Etesam, F, Azimi, AR, Benedict, R, Sahraian, MA, Validity and reliability of a Persian Translation of the Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS), The Clinical Neuropsychologist, 2012, 1–10.
  7. Alzheimer's Disease Neuroimaging Initiative Group. Detecting global and local hippocampal shape changes in Alzheimer's disease using statistical shape models. Neuroimage. 2012 Feb 1;59(3):2155-66.
  8. Alzheimer's Disease Neuroimaging Initiative Group. Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data. Neuroimage. 2012 Feb 1;59(3):2217-30.
  9. James A, Hough M, James S, Burge L, Winmill L, Nijhawan S, Matthews PM, Zarei M. Structural brain and neuropsychometric changes associated with pediatric bipolar disorder with psychosis. Bipolar Disord. 2011 Feb;13(1):16-27.
  10. James A, Hough M, James S, Winmill L, Burge L, Nijhawan S, Matthews PM, Zarei M. Greater white and grey matter changes associated with early cannabis use in adolescent-onset schizophrenia (AOS). Schizophr Res. 2011 May;128(1-3):91-7.
  11. Zarei M, Mataix-Cols D, Heyman I, Hough M, Doherty J, Burge L, Winmill L, Nijhawan S, Matthews PM, James A. Changes in gray matter volume and white matter microstructure in adolescents with obsessive-compulsive disorder. Biol Psychiatry. 2011 Dec 1;70(11):1083-90.
  12.  Eshaghi A, Riyahi-Alam S, Roostaei T, Haeri G, Aghsaei A, Aidi MR, Pouretemad HR, Zarei M, Farhang S, Saeedi R, Nazeri A, Ganjgahi H, Etesam F, Azimi AR, Benedict RH, Sahraian MA. Validity and Reliability of a Persian Translation of the Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS). Clin Neuropsychol. 2012 Jun 11.
  13. Ibarretxe-Bilbao N, Zarei M, Junque C, Marti MJ, Segura B, Vendrell P, Valldeoriola F, Bargallo N, Tolosa E. Dysfunctions of cerebral networks precede recognition memory deficits in early Parkinson's disease. Neuroimage. 2011 Jul 15;57(2):589-97.
  14. Pouretemad HR, Khatibi A, Zarei M, Stein J, Manifestations of developmental dyslexia in monolingual Persian speaking children. Arch Iran Medicine. 2011 Jul;14(4):259-65.
  15. Mahdavi A, Saberi H, Rezvanizadeh A, Lavasani A, Nilipour A, Zarei M, Oghabian MA , Developing Optimized fMRI Protocol for Clinical Use: Comparison of Different Language Paradigms, Arch Iran Med. 2010 May;13(3):223-9.
  16. Menke R., Jbabdi S, Miller K, Matthews PM, Zarei M, Connectivity-based Segmentation of the Substantia Nigra in Humans and its implications for Parkinson's Disease, Neuroimage. 2010 Oct 1;52(4):1175-80.
  17. Ibarretxe-Bilbao N, Junque C, Marti MJ, Valldeoriola F,Vendrell P, Bargallo N, Zarei M, Tolosa E, Olfactory impairment in Parkinson’s disease and white matter abnormalities in central olfactory areas. A voxel-based diffusion tensor imaging study, Movement Disorders 2010 Sep 15;25(12):1888-94
  18. Harirchian MH, Rezvanizadeh A, Fakhri M, Oghabian MA, Ghoreishi A, Zarei M, Firouznia K, Ghanaati H. Non-invasive brain mapping of motor-related areas of four limbs in patients with clinically isolated syndrome compared to healthy normal controls. J Clinical Neuroscience. 2010 Jun;17(6):736-41.
  19. Mahdavi A, Saberi H, Rezvanizadeh A, Lavasani A, Nilipour A, Zarei M, Oghabian MA, Cortical Representation of Persian Word Production: An fMRI Study. Archives of Iranian Medicine, 2010, May,13 (3) 223-229.
  20. Ibarretxe-Bilbao N, Junqué C., Tolosa E., Martí M.J., Valldeoriola F., Bargallo, N., Zarei M., Neuroanatomical correlates of impaired decision making and facial emotion recognition in early Parkinson’s disease, 2009, Eur J Neurosci. 2009 Sep;30(6):1162-71.
  21. Pouretemad HR, Khatibi, A., Ganjavi A, Shams J, Zarei M, Validation of Addenbrooke’s Cognitive Examination (ACE) in Native Persian Speaking Population, Dement Geriatr Cogn Disord. 2009;28(4):343-7.
  22. Zarei M, Pouretemad HR, Bak T, Hodges JR. Autobiographic memory in progressive supranuclear palsy. European J Neurology 2010 Feb;17(2):238-41.
  23. Zarei M., Patenaude B., Damoiseaux J.S., Morgese C, Smith S.M., Matthews PM., Barkhof F., Rombouts S.A.R.B., Sanz-Arigita E., Jenkinson M, Thalamic Degeneration in Alzheimer’s Disease: combining shape and connectivity, Neuroimage. 2010 Jan 1;49(1):1-8.
  24. Menke R., Scholtz J, Miller K, Deoni S, Jbabdi S, Matthews PM, Zarei M, MRI Characteristics of the Substantia Nigra in Parkinson’s Disease: A Combined Quantitative T1 and DTI Study, Neuroimage. 2009 Aug 15;47(2):435-440.
  25. Filippini N, Zarei M, Beckmann CF, Galluzzi S, Borsci G, Testa C, Bonetti M, Beltramello A, Orlandini A, Benussi L, Binetti G,, Frisoni GB. Age-related volume loss of interhemispheric prefrontal cortical tracts in cognitively normal APOE N4 carriers, 2008, J Magn Reson Imaging. 2009 May;29(5):1021-6
  26. Zarei M., Damoiseaux JS, Morgese C, Beckmann CF, Smith SM, Matthews PM, Scheltens Ph, Rombouts S.A.R.B., Barkhof F. Regional White Matter Integrity Differentiates between Vascular Dementia and Alzheimer‘s Disease, Stroke 2009;40(3):773-9.
  27. Damoiseaux JS, Smith SM, Witter MP, Arigita EJ, Barkhof F, Scheltens P, Stam CJ, Zarei M, Rombouts SA. White matter tract integrity in aging and Alzheimer's disease. Hum Brain Mapp. 2009 Apr;30(4):1051-9.
  28. Dargi F, Oghabian MA, Ahmadian A, Zadeh H, Zarei M, Boroomand A. Modified fast marching tractography algorithm and its ability to detect fibre crossing. Conf Proc IEEE Eng Med Biol Soc. 2007; 2007:319-22.
  29. Zarei M, Johansen-Berg H, Jenkinson M, Ciccarelli O, Thompson AJ, Matthews PM. Two-dimensional population map of cortical connections in the human internal capsule. J Magn Reson Imaging. 2007 Jan;25(1):48-54.
  30. Zarei M, Johansen-Berg H, Smith S, Ciccarelli O, Thompson AJ, Matthews PM. Functional anatomy of interhemispheric cortical connections in the human brain. J Anatomy. 2006;209(3):311-20.
  31. Zarei M. Clinical characteristics of cortical multiple sclerosis. J Neurol Sci. 2006;245(1-2):53-8.
  32. Dawe GS, Markevich VA, Zarei M, Grigoryan GA, Stephenson JD. Biphasic effects of atropine on sensory-evoked hippocampal rhythmical slow activity in urethane-anaesthetized rats. Zh Vyssh Nerv Deiat Im I P Pavlova. 2006; 56(2):264-73. 
  33. Zarei M, Johansen-Berg H, Ramnani N, Matthews PM, In vivo mapping of cortical connections in the human internal capsule and its implication in functional recovery after stroke, J Neurol Neurosurgery Psychiatry, 2005, 76:605
  34. Jacob S, Zarei M, Kenton A, Allroggen H. Gluten sensitivity and neuromyelitis optica: two case reports. J Neurol Neurosurg Psychiatry. 2005 Jul;76(7):1028-30.
  35. Zarei M, Johansen-Berg H, Matthews PM, Diffusion Tensor Imaging and Tractography in Clinical Neuroscience, Iranian Journal of Radiology, 2003, June, 45-52.
  36. Zarei M, Chandran S, Compston A, Hodges J. Cognitive presentation of multiple sclerosis: evidence for a cortical variant. J Neural Neurosurg Psychiatry. 2003 Jul;74(7):872-7.
  37. Zarei M, Immunological basis of neurological diseases, a review, Iranian Journal of Immunology, 2003 (1) 6-25
  38. Zarei M, Collins VP, Chandran S, Valler D, Higgins JN, Compston DA, Yates JR. Tuberous sclerosis presenting in late adult life. J Neurol Neurosurg Psychiatry. 2002 Oct;73(4):436-8.
  39. Zarei M, Anderson JR, Higgins JN, Manford MR. Cavernous sinus syndrome as the only manifestation of sarcoidosis. J Postgrad Med. 2002 Apr Jun;48(2):119-21.
  40. Zarei M, Stephenson JD. Effects of DSP4 and dizolcipine on connectivity of solid E19 cortical grafts to ablated SmI region of adult rats; an in vivo electrophysiological study. Brain Res. 2002 Aug 30;947(2):182-90.
  41. Zarei M, Nouraei SA, Caine D, Hodges JR, Carpenter RH. Neuropsychological and quantitative oculometric study of a case of sporadic Creutzfeldt-Jakob disease at predementia stage. J Neurol Neurosurg Psychiatry. 2002 Jul;73(1):56-8.
  42. Al-Adawi S, Dawe GS, Bonner A, Stephenson JD, Zarei M. Central noradrenergic blockade prevents autotomy in rat: implication for pharmacological prevention of postdenervation pain syndrome. Brain Res Bull. 2002 Mar 15;57(5):581-6.
  43. Zarei M, Letter to the Editor "Iranian National Health Survey: A Brief Report", Archives of Iranian Medicine, 2002; 5(4):280-281
  44. Zarei M, Raevsky VV, Dawe GS, Stephenson JD. Changes in sensitivity of cholinoceptors and adrenoceptors during transhemispheric cortical reorganisation in rat SmI. Brain Res. 2001 Jan 12;888(2):267-274.
  45. Zarei M, Morris J, Aachi V, Gregory R, Meanock C, Brito-Babapulle F. Acute isolated cerebral mucormycosis in a patient with high grade non-Hodgkins lymphoma. Eur J Neurol. 2000 Jul;7(4):443-7.
  46. Zarei M, Stephenson JD. Transhemispheric cortical reorganization in rat SmI and involvement of central noradrenergic system. Brain Res. 2000 Jul 7;870(1-2):142-9.
  47. Raevsky VV, Dawe GS, Zarei M, Stephenson JD (1996) Age-dependent acetylcholine and noradrenaline sensitivity of somatosensory cortical neurons in the rat. Proceedings of Russian Academy of Medical Sciences.
  48. Zarei M, Stephenson JD. Ipsilateral and bilateral receptive fields in rat primary somatosensory cortex. Neuroreport. 1996 Jan 31;7(2):647-51.


Zarei M. and Fakharian E. 1988, (English to Persian) “The Neurosciences and Behaviour: An Introduction” by Dale Atrens and A. Curthoys. Academic Press. Tehran.